Skin Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Skin Cancer, including details on identification, causes, prevention, treatment.

Cutaneous epithelioid angioleiomyoma with clear-cell change.

Liu JY, Liao SL, Zheng J

Department of Pathology, Health Science Center of Peking University, Beijing, China. liujianying@hsc.pku.edu.cn

Epithelioid angioleiomyoma is rare in the skin and subcutis. We report here an unusual case of epithelioid angioleiomyoma with prominent clear-cell change. Smooth-muscle differentiation was confirmed by immunostains. The extensive clear-cell change in epithelial cells and the marked hyalinization and calcification made the histologic differential diagnosis challenging. Epithelioid angioleiomyoma shares some histologic characteristics with glomus tumors and seems to be an intermediate entity between angioleiomyomas and glomus tumors.

Published 6 April 2007 in Am J Dermatopathol, 29(2): 190-3.
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