Skin Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Skin Cancer, including details on identification, causes, prevention, treatment.

Chemopreventative thoughts for photodynamic therapy.

Bissonnette R

Innovaderm Research, 1851 Sherbrooke Street East, Suite 502, Montreal, QC H2K 4L5, Canada. rbissonnette@innovaderm.ca

The concept of skin cancer prevention with photodynamic therapy has evolved over the past few years to include large surface application of aminolevulinic acid or methyl aminolevulinate followed by light exposure to prevent the development of new lesions. Pre-clinical studies using various mouse models have shown that large surface photodynamic therapy can prevent the appearance of actinic keratoses, squamous cell carcinomas, and basal cell carcinomas. Recent clinical studies also suggest that large surface photodynamic therapy can prevent the development of actinic keratoses and possibly skin cancer.

Published 27 November 2006 in Dermatol Clin, 25(1): 95-100.
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